Comparison of susceptibility-weighted imaging and susceptibility map-weighted imaging for the diagnosis of Parkinsonism with nigral hyperintensity

ObjectiveTo determine whether susceptibility map-weighted imaging (SMWI) was superior to conventional susceptibility-weighted (SWI) in the diagnosis of Parkinson’s disease (PD) and its correlation with 123I-2bcarbomethoxy-3b-(4-iodophenyl)-N-(3-fluoropropyl)-nortropane single photon emission computerized tomography (123I-FP-CIT SPECT).MethodsBetween May 2017 February 2018, 125 consecutive patients diagnosed idiopathic PD, vascular pseudoparkinsonism, essential tremor, or drug-induced parkinsonism who underwent 123I-FP-CIT SPECT 3 T SWI on same day within months were included this retrospective study. In all patients, SMWI images generated from images. On both MRIs, two neuroradiologists independently evaluated status nigral hyperintensity each side substantia nigra. Inter-observer agreements for tested. Using consensus reading, concordance between SWI, SMWI, evaluated, diagnostic performance PD compared.ResultsInter-observer agreement higher (right, κ = 0.919; left, 0.984) than 0.918; 0.902). (right 67.2 %, left 68.0 %) showed a rate results 60.0 59.2 %). (area under curve [AUC], 0.791) provided significantly (AUC, 0.720; P 0.0005).ConclusionSMWI may be assessment tool an improved modality suspected PD.